Europe's leading CRO in
food and feed safety
Biosafe helps new sustainable food & feed solutions get approved and reach the European market. From laboratory to legislation to the latest intelligence.
Biosafe is a Contract Research Organization (CRO) integrating scientific laboratory work, bioanalysis and EU regulation guidance.
The interpretation of European Food Safety Authorities (EFSA) guidelines are at the heart of the work of our consulting professors, who are specialized in EU requirements. We perform research and product safety assessments from the product development stage onwards. When only safe products are taken forward in the development process, you can avoid unnecessary costs and focus on the promising products.
Genome sequencing and bioinformatics
Our professionals are vastly experienced in whole-genome sequencing and our pipeline is optimized to fulfil the safety assessment requirements of EFSA whether it's analyzing DNA for GMOs, AMR or anything else.
EU regulatory consulting
We have extensive expertise and experience in what the EU, the European Commission and EFSA demand of the safety of industrial microbiology products. Our consulting team can advise you on a wide range of topics on food safety and guide what you should be doing next.
Antimicrobial susceptibility test (MIC)
We perform over 100 antimicrobial susceptibility tests (MIC) each year for both aerobic and anaerobic bacteria.
Production of antimicrobials
We conduct thorough assessment of antimicrobial production by disc diffusion method, following EFSA guidance.
Our laboratory performs in vitro cytotoxicity tests with Vero cells, as recommended by EFSA.
Absence of cells in fermentation products
We successfully verify the absence of cells in fermentation products according to appropriate principles and EFSA requirements.
Presence of DNA in fermentation products
Our team tests the presence of DNA in fermentation products with strain-specific PCR and according to EFSA requirements.
Pulsed Field Gel Electrophoresis (PFGE)
We conduct pulsed field gel electrophoresis (PFGE) to verify the presence of a specific microbial feed additive in nonsterile materials.
In vitro efficacy
We have developed and validated in vitro efficacy methods to cover the various effects that microbial feed additives can have on feed products.
SDS-polyacrylamide gel electrophoresis
By using SDS PAGE, we obtain an overview of food enzymes for regulatory purposes, while looking for their purity and batch-to-batch variations.
Genetic toxicity: Bacterial reverse mutation test (OECD 471)
We use the bacterial reverse mutation test (Ames) to successfully assess genotoxicity in food and feed products, additives, enzymes, and more.
Biogenic amine analysis
We can provide a Biogenic Amine Analysis based on a bioinformatic search of the genome, as well as a laboratory in vitro analysis of BA production.
Quantitative Polymerase Chain Reaction (qPCR) couples amplification of a DNA sequence with quantification of the concentration of that DNA species.