Characterisation of a microorganism

Bioinformatics provides genome-based safety assessments of microorganisms. Usually, the project starts with DNA isolation and continues to whole genome sequencing and assembly and annotation of the genome. We can also work with sequence data provided by the customer.

A pipeline has been developed in-house to obtain the needed information from the genome in a cost-effective manner. As bioinformatics is a fast-developing field, no exact methods are recommended by EFSA or by other authorities. Biosafe Ltd is closely monitoring possible changes in the requirements and databases and adjusts the pipeline without delay. For all sequencing projects we take care that the data is appropriate for the purpose of the analysis and data quality meets the requirements of authorities.

Biosafe has assessed hundreds of genomes and has gained valuable knowledge about the characteristics of common industrial microorganisms, and what can be expected and not expected during the hazard identification step. The study reports include expert data interpretation in the light of current scientific knowledge and are ready to be delivered to the authorities as is.